ID 1.1.1.346 DE 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming). AN 2,5-diketo-D-gluconate-reductase. CA 2-dehydro-L-idonate + NADP(+) = 2,5-didehydro-D-gluconate + H(+) + NADPH. CC -!- The enzyme is involved in ketogluconate metabolism, and catalyzes the CC reaction in vivo in the reverse direction to that shown. CC -!- It is used in the commercial microbial production of ascorbate. cf. CC EC 1.1.1.274. DR P06632, DKGA_CORSC ; Q8XBT6, DKGA_ECO57 ; P58744, DKGA_SALTI ; DR Q8ZM06, DKGA_SALTY ; Q8ZI40, DKGA_YERPE ; Q8X7Z7, DKGB_ECO57 ; DR P30863, DKGB_ECOLI ; Q8Z988, DKGB_SALTI ; Q8ZRM7, DKGB_SALTY ; DR Q8ZH36, DKGB_YERPE ; //