ID 1.1.1.346 DE 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming). AN 2,5-diketo-D-gluconate-reductase. CA 2-dehydro-L-idonate + NADP(+) = 2,5-didehydro-D-gluconate + NADPH + H(+). CC -!- The enzyme is involved in ketogluconate metabolism, and catalyzes the CC reaction in vivo in the reverse direction to that shown. CC -!- It is used in the commercial microbial production of ascorbate. cf. CC EC 1.1.1.274. DR P06632, DKGA_CORSC ; Q46857, DKGA_ECOLI ; P30863, DKGB_ECOLI ; //