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ENZYME entry: EC 1.1.1.348

Accepted Name
(3R)-2'-hydroxyisoflavanone reductase.
Alternative Name(s)
vestitone reductase.
Reaction catalysed
a (3R,4R)-4,2'-dihydroxyisoflavan + NADP(+) <=> a (3R)-2'-hydroxyisoflavanone + H(+) + NADPH
Comment(s)
  • This plant enzyme participates in the biosynthesis of the pterocarpan phytoalexins medicarpin, maackiain, and several forms of glyceollin.
  • The enzyme has a strict stereo specificity for the 3R-isoflavanones.
  • Formerly EC 1.1.1.246.
Cross-references
BRENDA1.1.1.348
EC2PDB1.1.1.348
ExplorEnz1.1.1.348
PRIAM enzyme-specific profiles1.1.1.348
KEGG Ligand Database for Enzyme Nomenclature1.1.1.348
IUBMB Enzyme Nomenclature1.1.1.348
IntEnz1.1.1.348
MEDLINEFind literature relating to 1.1.1.348
MetaCyc1.1.1.348
Rhea expert-curated reactions1.1.1.348
UniProtKB/Swiss-Prot
Q40316, VESTR_MEDSA

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