ID 1.1.1.351 DE Phosphogluconate dehydrogenase (NAD(P)(+)-dependent, decarboxylating). CA 6-phospho-D-gluconate + NAD(P)(+) = D-ribulose 5-phosphate + CO(2) + CA NAD(P)H. CC -!- The enzyme participates in the oxidative branch of the pentose CC phosphate pathway, whose main purpose is to produce reducing power CC and pentose for biosynthetic reactions. CC -!- Unlike EC 1.1.1.44, it is not specific for NADP(+) and can accept CC both cofactors with similar efficiency. CC -!- Cf. EC 1.1.1.343. //