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ENZYME

ENZYME entry: EC 1.1.1.352

PURL: https://purl.expasy.org/enzyme/EC/1.1.1.352
Accepted Name
5'-hydroxyaverantin dehydrogenase
Alternative Name(s)
HAVN dehydrogenase
Reaction catalysed
  • (1'S,5'S)-5'-hydroxyaverantin + NAD(+) = (S)-5'-oxoaverantin + NADH + H(+)
  • (1'S,5'R)-5'-hydroxyaverantin + NAD(+) = (S)-5'-oxoaverantin + NADH + 2 H(+)
Comment(s)
  • Isolated from the aflatoxin-producing mold Aspergillus parasiticus.
  • Involved in aflatoxin biosynthesis.
  • 5'-oxoaverantin will spontaneously form averufin by intramolecular ketalisation. cf. EC 4.2.1.142.
Cross-references
BRENDA1.1.1.352
EC2PDB1.1.1.352
ExplorEnz1.1.1.352
KEGG Ligand Database for Enzyme Nomenclature1.1.1.352
IUBMB Enzyme Nomenclature1.1.1.352
MEDLINEFind literature relating to 1.1.1.352
MetaCyc1.1.1.352
Rhea expert-curated reactions1.1.1.352
UniProtKB/Swiss-Prot
M2YJK1, ADHA_DOTSNP87017, AFLH_ASPPUA0A1U8QGV2, STCG_EMENI

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