ID   1.1.1.357
DE   3alpha-hydroxysteroid 3-dehydrogenase.
AN   3alpha-hydroxysteroid dehydrogenase.
CA   (1) a 3alpha-hydroxysteroid + NADP(+) = a 3-oxosteroid + H(+) + NADPH.
CA   (2) a 3alpha-hydroxysteroid + NAD(+) = a 3-oxosteroid + H(+) + NADH.
CC   -!- The enzyme acts on multiple 3alpha-hydroxysteroids, such as
CC       androsterone and 5 alpha-dihydrotestosterone.
CC   -!- The mammalian enzymes are involved in inactivation of steroid
CC       hormones, while the bacterial enzymes are involved in steroid
CC       degradation.
CC   -!- This entry stands for enzymes whose stereo-specificity with respect
CC       to NAD(+) or NADP(+) is not known (cf. EC 1.1.1.50 and EC 1.1.1.213).
DR   Q04828, AK1C1_HUMAN;  Q95JH7, AK1C1_MACFA;  Q95JH6, AK1C1_MACFU;
DR   Q5REQ0, AK1C1_PONAB;  P52895, AK1C2_HUMAN;  P42330, AK1C3_HUMAN;
DR   Q5R7C9, AK1C3_PONAB;  P17516, AK1C4_HUMAN;  Q95JH5, AK1C4_MACFA;
DR   Q95JH4, AK1C4_MACFU;
//