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ENZYME entry: EC 1.1.1.358

Accepted Name
2-dehydropantolactone reductase.
Alternative Name(s)
2-dehydropantoyl-lactone reductase.
2-ketopantoyl lactone reductase.
2-oxopantoyl lactone reductase.
ketopantoyl lactone reductase.
Reaction catalysed
(R)-pantolactone + NADP(+) <=> 2-dehydropantolactone + H(+) + NADPH
Comment(s)
  • The enzyme participates in an alternative pathway for biosynthesis of (R)-pantothenate (vitamin B5).
  • This entry covers enzymes whose stereo specificity for NADP(+) is not known (cf. EC 1.1.1.168 and EC 1.1.1.214).
Cross-references
BRENDA1.1.1.358
EC2PDB1.1.1.358
ExplorEnz1.1.1.358
PRIAM enzyme-specific profiles1.1.1.358
KEGG Ligand Database for Enzyme Nomenclature1.1.1.358
IUBMB Enzyme Nomenclature1.1.1.358
IntEnz1.1.1.358
MEDLINEFind literature relating to 1.1.1.358
MetaCyc1.1.1.358
Rhea expert-curated reactions1.1.1.358
UniProtKB/Swiss-Prot
Q76L36, CPRC2_CANPA

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