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ENZYME entry: EC 1.1.1.359

Accepted Name
aldose 1-dehydrogenase [NAD(P)(+)].
Reaction catalysed
  • an aldopyranose + NADP(+) <=> aldono-1,5-lactone + H(+) + NADPH
  • an aldopyranose + NAD(+) <=> aldono-1,5-lactone + H(+) + NADH
Comment(s)
  • The enzyme from the archaeon Sulfolobus solfataricus shows broad specificity toward aldoses (D-glucose, D-galactose, D-xylose, L-arabinose, 6-deoxy-D-glucose, D-fucose) and can utilize NAD(+) and NADP(+) with similar catalytic efficiency.
  • It is involved in aldose catabolism via the branched variant of the Entner-Doudoroff pathway.
Cross-references
BRENDA1.1.1.359
EC2PDB1.1.1.359
ExplorEnz1.1.1.359
PRIAM enzyme-specific profiles1.1.1.359
KEGG Ligand Database for Enzyme Nomenclature1.1.1.359
IUBMB Enzyme Nomenclature1.1.1.359
IntEnz1.1.1.359
MEDLINEFind literature relating to 1.1.1.359
MetaCyc1.1.1.359
Rhea expert-curated reactions1.1.1.359
UniProtKB/Swiss-Prot
O93715, GLCDH_SACSO

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