ID   1.1.1.364
DE   dTDP-4-dehydro-6-deoxy-alpha-D-gulose 4-ketoreductase.
AN   dTDP-4-dehydro-6-deoxygulose reductase.
CA   (1) dTDP-6-deoxy-alpha-D-allose + NAD(+) = dTDP-4-dehydro-6-deoxy-alpha-
CA   D-allose + H(+) + NADH.
CA   (2) dTDP-6-deoxy-alpha-D-allose + NADP(+) = dTDP-4-dehydro-6-deoxy-alpha-
CA   D-allose + H(+) + NADPH.
CC   -!- The enzyme forms an activated deoxy-alpha-D-allose, which is
CC       converted to mycinose after attachment to the aglycones of several
CC       macrolide antibiotics, including tylosin, chalcomycin,
CC       dihydrochalcomycin, and mycinamicin II.
DR   Q5SFA6, CHMD_STRBI ;  Q331Q7, GERKI_STRSQ;
//