ID 1.1.1.393 DE 3beta-hydroxycholanate 3-dehydrogenase (NADP(+)). AN 3beta-hydroxysteroid dehydrogenase. CA 3-oxo-5beta-cholan-24-oate + H(+) + NADPH = isolithocholate + NADP(+). CC -!- This bacterial enzyme is involved, along with EC 1.1.1.52 or CC EC 1.1.1.392, in the modification of secondary bile acids to form CC 3beta-bile acids (also known as iso-bile acids). CC -!- The enzyme catalyzes the reaction in the reduction direction in vivo. CC -!- Also acts on related 3-oxo bile acids. cf. EC 1.1.1.391. DR A7AZH2, 3BHDP_RUMGV; //