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ENZYME

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ENZYME entry: EC 1.1.1.395

Accepted Name
3alpha-hydroxybile acid CoA 3-dehydrogenase
Reaction catalysed
a 3alpha-hydroxy bile acid CoA + NAD(+) = a 3-oxo bile acid CoA + H(+) + NADH
Comment(s)
  • This bacterial enzyme is involved in the 7-dehydroxylation process associated with bile acid degradation.
  • The enzyme has very little activity with unconjugated bile acid substrates.
  • It has similar activity with choloyl-CoA, chenodeoxycholoyl-CoA, deoxycholoyl-CoA, and lithocholoyl-CoA.
  • Formerly EC 1.17.1.6, EC 1.17.98.1 and EC 1.17.99.5.
Cross-references
BRENDA1.1.1.395
EC2PDB1.1.1.395
ExplorEnz1.1.1.395
PRIAM enzyme-specific profiles1.1.1.395
KEGG Ligand Database for Enzyme Nomenclature1.1.1.395
IUBMB Enzyme Nomenclature1.1.1.395
IntEnz1.1.1.395
MEDLINEFind literature relating to 1.1.1.395
MetaCyc1.1.1.395
Rhea expert-curated reactions1.1.1.395
UniProtKB/Swiss-Prot
P07914, BAIA1_CLOSVP19337, BAIA2_CLOSV

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