ENZYME entry: EC 1.1.1.397
Accepted Name |
Beta-methylindole-3-pyruvate reductase.
|
Reaction catalysed |
(2S,3R)-2-hydroxy-3-(indol-3-yl)butanoate + NAD(+) <=> (R)-3-(indol-3-yl)-2-oxobutanoate + NADH |
Comment(s) |
The enzyme, characterized from the bacterium Streptomyces griseus,
participates in the biosynthesis of indolmycin, an antibacterial drug
that inhibits the bacterial EC 6.1.1.2.
|
Cross-references |
BRENDA | 1.1.1.397 |
EC2PDB | 1.1.1.397 |
ExplorEnz | 1.1.1.397 |
PRIAM enzyme-specific profiles | 1.1.1.397 |
KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.397 |
IUBMB Enzyme Nomenclature | 1.1.1.397 |
IntEnz | 1.1.1.397 |
MEDLINE | Find literature relating to 1.1.1.397 |
MetaCyc | 1.1.1.397 |
UniProtKB/Swiss-Prot |
|
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