ID   1.1.1.399
DE   2-oxoglutarate reductase.
CA   (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH.
CC   -!- The enzyme catalyzes a reversible reaction.
CC   -!- The enzyme from the bacterium Peptoniphilus asaccharolyticus is
CC       specific for (R)-2-hydroxyglutarate.
CC   -!- The SerA enzyme from Escherichia coli can also accept (S)-2-
CC       hydroxyglutarate with a much higher Km, and also catalyzes the
CC       activity of EC 1.1.1.95.
DR   D2RJU7, HGDH_ACIFV ;  P40510, SER33_YEAST;  P35136, SERA_BACSU ;
DR   Q5EAD2, SERA_BOVIN ;  Q54UH8, SERA_DICDI ;  P0A9T2, SERA_ECO57 ;
DR   P0A9T1, SERA_ECOL6 ;  P0A9T0, SERA_ECOLI ;  P43885, SERA_HAEIN ;
DR   O43175, SERA_HUMAN ;  Q60HD7, SERA_MACFA ;  P0A545, SERA_MYCBO ;
DR   O33116, SERA_MYCLE ;  P9WNX2, SERA_MYCTO ;  P9WNX3, SERA_MYCTU ;
DR   A5A6P1, SERA_PANTR ;  A5GFY8, SERA_PIG   ;  Q5R7M2, SERA_PONAB ;
DR   P87228, SERA_SCHPO ;  P0A9T3, SERA_SHIFL ;  P73821, SERA_SYNY3 ;
DR   P40054, SERA_YEAST ;
//