ID 1.1.1.413 DE A-factor type gamma-butyrolactone 1'-reductase (1S-forming). CA a (3R,4R)-3-[(1S)-1-hydroxyalkyl]-4-(hydroxymethyl)oxolan-2-one + NADP(+) CA = a (3R,4R)-3-alkanoyl-4-(hydroxymethyl)oxolan-2-one + H(+) + NADPH. CC -!- The enzyme, which is found in bacteria that produce virginiae- CC butanolide (VB) type gamma-butyrolactone autoregulators, reduces its CC substrate stereospecifically, forming a hydroxyl group in the (S) CC configuration. DR Q9LBV3, BARS1_STRVG; //