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ENZYME

ENZYME entry: EC 1.1.1.421

Accepted Name
D-apionate oxidoisomerase
Reaction catalysed
D-apionate + NAD(+) <=> 3-oxoisoapionate + H(+) + NADH
Comment(s)
  • The enzyme, characterized from several bacterial species, participates in the degradation of D-apionate.
  • The reaction involves migration of a hydroxymethyl group from position 3 to position 2 and oxidation of the 3-hydroxyl group.
  • Stereospecificity of the product, 3-oxoisoapionate, has not been determined.
Cross-references
BRENDA1.1.1.421
EC2PDB1.1.1.421
ExplorEnz1.1.1.421
PRIAM enzyme-specific profiles1.1.1.421
KEGG Ligand Database for Enzyme Nomenclature1.1.1.421
IUBMB Enzyme Nomenclature1.1.1.421
IntEnz1.1.1.421
MEDLINEFind literature relating to 1.1.1.421
MetaCyc1.1.1.421
Rhea expert-curated reactions1.1.1.421
UniProtKB/Swiss-Prot
B9JK75, APNO_AGRRKC0CMQ7, APNO_BLAHSF8GV06, APNO_CUPNN
Q6D8V3, APNO_PECAS

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