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ENZYME

ENZYME entry: EC 1.1.1.437

Accepted Name
5-dehydrofumagillol 5-reductase
Reaction catalysed
fumagillol + NADP(+) <=> 5-dehydrofumagillol + H(+) + NADPH
Comment(s)
  • The enzyme, characterized from the mold Aspergillus fumigatus, participates in the biosynthesis of the meroterpenoid fumagillin.
  • It is a partial polyketide synthase (PKS) consisting of only a dehydratase (DH) and a ketoreductase (KR) domain.
Cross-references
BRENDA1.1.1.437
EC2PDB1.1.1.437
ExplorEnz1.1.1.437
PRIAM enzyme-specific profiles1.1.1.437
KEGG Ligand Database for Enzyme Nomenclature1.1.1.437
IUBMB Enzyme Nomenclature1.1.1.437
IntEnz1.1.1.437
MEDLINEFind literature relating to 1.1.1.437
MetaCyc1.1.1.437
Rhea expert-curated reactions1.1.1.437
UniProtKB/Swiss-Prot
Q4WAZ4, FMAH_ASPFU

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