ENZYME entry: EC 1.1.1.50
| Accepted Name |
|---|
| 3-alpha-hydroxysteroid 3-dehydrogenase (Si-specific).
|
| Alternative Name(s) |
|---|
| 3-alpha-HSD. |
| 3-alpha-hydroxysteroid 3-dehydrogenase (B-specific). |
| 3-alpha-hydroxysteroid dehydrogenase (B-specific). |
| Hydroxyprostaglandin dehydrogenase. |
| Reaction catalysed |
|---|
| A 3-alpha-hydroxysteroid + NAD(P)(+) <=> a 3-oxosteroid + NAD(P)H |
| Comment(s) |
|---|
- The enzyme acts on androsterone and other 3-alpha-hydroxysteroids and
on 9-, 11- and 15-hydroxyprostaglandin.
- Si-specific with respect to NAD(+) or NADP(+) (cf. EC 1.1.1.213).
|
| Cross-references |
|---|
| PROSITE | PDOC00061 |
| BRENDA | 1.1.1.50 |
| EC2PDB | 1.1.1.50 |
| ExplorEnz | 1.1.1.50 |
| PRIAM enzyme-specific profiles | 1.1.1.50 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.50 |
| IUBMB Enzyme Nomenclature | 1.1.1.50 |
| IntEnz | 1.1.1.50 |
| MEDLINE | Find literature relating to 1.1.1.50 |
| MetaCyc | 1.1.1.50 |
| UniProtKB/Swiss-Prot |
|
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