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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.1.1.85

Accepted Name
3-isopropylmalate dehydrogenase.
Alternative Name(s)
Beta-IPM dehydrogenase.
Beta-isopropylmalate dehydrogenase.
IMDH.
Reaction catalysed
(2R,3S)-3-isopropylmalate + NAD(+) <=> 4-methyl-2-oxopentanoate + CO(2) + NADH
Cross-references
PROSITEPDOC00389
BRENDA1.1.1.85
EC2PDB1.1.1.85
ExplorEnz1.1.1.85
PRIAM enzyme-specific profiles1.1.1.85
KEGG Ligand Database for Enzyme Nomenclature1.1.1.85
IUBMB Enzyme Nomenclature1.1.1.85
IntEnz1.1.1.85
MEDLINEFind literature relating to 1.1.1.85
MetaCyc1.1.1.85
UniProtKB/Swiss-Prot
C9K7B7, AMT6_ALTAL;  S3DB74, GLOI_GLAL2;  K0E689, HTYC_ASPRU;  
Q9SA14, LEU31_ARATH;  Q7WNM3, LEU31_BORBR;  Q89XA0, LEU31_BRADU;  
Q47HR1, LEU31_DECAR;  P93832, LEU32_ARATH;  Q7WKH4, LEU32_BORBR;  
Q89X19, LEU32_BRADU;  Q479H7, LEU32_DECAR;  Q9FMT1, LEU33_ARATH;  
P87256, LEU3A_ASPNG;  P87257, LEU3B_ASPNG;  Q6FEV6, LEU3_ACIAD;  
Q56268, LEU3_ACIFR;  Q12545, LEU3_ACRCH;  P24404, LEU3_AGRFC;  
Q5E857, LEU3_ALIF1;  Q2IJK7, LEU3_ANADE;  Q3M8T9, LEU3_ANAVT;  
O66607, LEU3_AQUAE;  O29627, LEU3_ARCFU;  Q5P1J6, LEU3_AROAE;  
Q00412, LEU3_ARTPT;  O60027, LEU3_ASHGO;  P96197, LEU3_AZOVI;  
Q81T67, LEU3_BACAN;  Q73B99, LEU3_BACC1;  P05644, LEU3_BACCA;  
P12010, LEU3_BACCO;  Q81G11, LEU3_BACCR;  Q63DX7, LEU3_BACCZ;  
Q5LAB4, LEU3_BACFN;  P54354, LEU3_BACFR;  Q9K8E9, LEU3_BACHD;  
Q6HLF2, LEU3_BACHK;  Q65GI9, LEU3_BACLD;  P41019, LEU3_BACMD;  
Q5WEN4, LEU3_BACSK;  P05645, LEU3_BACSU;  Q8A6M0, LEU3_BACTN;  
C5C2I9, LEU3_BEUC1;  B3DTF8, LEU3_BIFLD;  Q8G500, LEU3_BIFLO;  
B7GUI8, LEU3_BIFLS;  Q8NKB8, LEU3_BLAAD;  Q7VQJ7, LEU3_BLOFL;  
Q493R1, LEU3_BLOPB;  Q2KYL5, LEU3_BORA1;  Q7W929, LEU3_BORPA;  
Q7VY73, LEU3_BORPE;  P29102, LEU3_BRANA;  Q2YL58, LEU3_BRUA2;  
Q579B1, LEU3_BRUAB;  Q8YCX4, LEU3_BRUME;  Q8FVF3, LEU3_BRUSU;  
P56933, LEU3_BUCAI;  O85064, LEU3_BUCAP;  P59515, LEU3_BUCBP;  
Q5WPZ9, LEU3_BUCCC;  O85071, LEU3_BUCDN;  Q9EVG3, LEU3_BUCML;  
P59027, LEU3_BUCPS;  P48572, LEU3_BUCRP;  O31292, LEU3_BUCTS;  
Q9EVG6, LEU3_BUCUA;  Q9EVE1, LEU3_BUCUD;  Q9EVH5, LEU3_BUCUE;  
Q9EVH8, LEU3_BUCUH;  Q9AQC8, LEU3_BUCUL;  Q9EVG9, LEU3_BUCUM;  
Q9EVI7, LEU3_BUCUN;  Q9EVI1, LEU3_BUCUO;  Q9EVI4, LEU3_BUCUS;  
Q393X4, LEU3_BURL3;  Q845W3, LEU3_BURM1;  Q62AI9, LEU3_BURMA;  
Q3JKG9, LEU3_BURP1;  Q63JL2, LEU3_BURPS;  Q2T7H6, LEU3_BURTA;  
Q8RDK0, LEU3_CALS4;  Q9PLW0, LEU3_CAMJE;  Q5HS77, LEU3_CAMJR;  
P87186, LEU3_CANAX;  Q01987, LEU3_CANBO;  O14429, LEU3_CANGA;  
Q6PY58, LEU3_CANHU;  P07139, LEU3_CANMA;  Q3AEQ2, LEU3_CARHZ;  
Q9ABN3, LEU3_CAUVC;  Q3APC4, LEU3_CHLCH;  Q3B595, LEU3_CHLL7;  
P59028, LEU3_CHLTE;  Q1QUR0, LEU3_CHRSD;  Q7NUC2, LEU3_CHRVO;  
A5CPZ4, LEU3_CLAM3;  B0RIP4, LEU3_CLAMS;  Q97EE2, LEU3_CLOAB;  
P31958, LEU3_CLOPA;  Q47WG3, LEU3_COLP3;  C3PFX5, LEU3_CORA7;  
Q6NHM7, LEU3_CORDI;  Q8FPV5, LEU3_COREF;  A4QDP9, LEU3_CORGB;  
P94631, LEU3_CORGL;  Q4JUQ0, LEU3_CORJK;  C4LJH3, LEU3_CORK4;  
B1VG35, LEU3_CORU7;  Q1LKH7, LEU3_CUPMC;  Q46YW0, LEU3_CUPNJ;  
P08791, LEU3_CYBJA;  Q6B458, LEU3_DEBHA;  Q3Z896, LEU3_DEHM1;  
Q3ZXI7, LEU3_DEHMC;  Q1IZK2, LEU3_DEIGD;  Q9RTH9, LEU3_DEIRA;  
Q30WD0, LEU3_DESAG;  Q24XT2, LEU3_DESHY;  Q6ANR1, LEU3_DESPS;  
Q726X1, LEU3_DESVH;  Q9HDQ5, LEU3_DIURU;  Q8X9Z9, LEU3_ECO57;  
Q8FL76, LEU3_ECOL6;  P30125, LEU3_ECOLI;  Q1RGC4, LEU3_ECOUT;  
Q2J6V8, LEU3_FRACC;  A8L554, LEU3_FRASN;  Q5KWJ4, LEU3_GEOKA;  
Q39Y29, LEU3_GEOMG;  Q748X2, LEU3_GEOSL;  Q7NFH4, LEU3_GLOVI;  
Q5FUG5, LEU3_GLUOX;  Q4QLS3, LEU3_HAEI8;  P43860, LEU3_HAEIN;  
Q2SJD6, LEU3_HAHCH;  D4GYE8, LEU3_HALVD;  Q7VH33, LEU3_HELHP;  
Q31HI0, LEU3_HYDCU;  Q28W67, LEU3_JANSC;  P23390, LEU3_KLULA;  
P41766, LEU3_KLUMA;  P41926, LEU3_KODOH;  Q02143, LEU3_LACLA;  
Q6AEP6, LEU3_LEIXX;  Q72RH7, LEU3_LEPIC;  P24015, LEU3_LEPIN;  
Q92A27, LEU3_LISIN;  Q71Y34, LEU3_LISMF;  Q8Y5R8, LEU3_LISMO;  
Q2VZV2, LEU3_MAGSA;  Q65V05, LEU3_MANSM;  Q606F4, LEU3_METCA;  
Q58130, LEU3_METJA;  O27441, LEU3_METTH;  Q2RGA0, LEU3_MOOTA;  
A0QJC2, LEU3_MYCA1;  P94929, LEU3_MYCBO;  A1KMY9, LEU3_MYCBP;  
C1AGB0, LEU3_MYCBT;  A4TE12, LEU3_MYCGI;  B8ZS15, LEU3_MYCLB;  
O33117, LEU3_MYCLE;  B2HIH1, LEU3_MYCMM;  Q73VI1, LEU3_MYCPA;  
A3PXQ2, LEU3_MYCSJ;  A1UE98, LEU3_MYCSK;  Q1BAR4, LEU3_MYCSS;  
A5U706, LEU3_MYCTA;  P9WKK8, LEU3_MYCTO;  P9WKK9, LEU3_MYCTU;  
A0PPY6, LEU3_MYCUA;  A1T6Z4, LEU3_MYCVP;  Q5F8T6, LEU3_NEIG1;  
P50180, LEU3_NEILA;  Q9JU79, LEU3_NEIMA;  Q9JZI9, LEU3_NEIMB;  
P34738, LEU3_NEUCR;  Q82WI6, LEU3_NITEU;  Q2Y7Q8, LEU3_NITMU;  
Q3JCC4, LEU3_NITOC;  Q3SNU3, LEU3_NITWN;  Q5YRX2, LEU3_NOCFA;  
Q8YXA2, LEU3_NOSS1;  Q2G4X5, LEU3_NOVAD;  Q8EN68, LEU3_OCEIH;  
Q9CJN6, LEU3_PASMU;  Q6D0G7, LEU3_PECAS;  Q3A3B2, LEU3_PELCD;  
Q4FP17, LEU3_PELUB;  O59930, LEU3_PHACH;  Q7N128, LEU3_PHOLL;  
Q6LV25, LEU3_PHOPR;  P34733, LEU3_PICAN;  O94114, LEU3_PICST;  
Q31B91, LEU3_PROM9;  Q7VC80, LEU3_PROMA;  Q7V842, LEU3_PROMM;  
Q7V1R9, LEU3_PROMP;  Q46LE2, LEU3_PROMT;  Q48K97, LEU3_PSE14;  
Q51375, LEU3_PSEAE;  Q4KF05, LEU3_PSEF5;  Q3IJS3, LEU3_PSEHT;  
Q3KF21, LEU3_PSEPF;  Q88LE5, LEU3_PSEPK;  Q884C0, LEU3_PSESM;  
Q4ZUZ4, LEU3_PSEU2;  Q4FRV0, LEU3_PSYA2;  Q1QAF5, LEU3_PSYCK;  
Q8XXX5, LEU3_RALSO;  Q2K2V0, LEU3_RHIEC;  Q1MA50, LEU3_RHIL3;  
Q98E57, LEU3_RHILO;  Q92KY8, LEU3_RHIME;  Q7UIE1, LEU3_RHOBA;  
C0ZXM4, LEU3_RHOE4;  Q21XI1, LEU3_RHOFT;  Q0S2H1, LEU3_RHOJR;  
C1B2M3, LEU3_RHOOB;  Q2J3B4, LEU3_RHOP2;  Q6ND82, LEU3_RHOPA;  
Q21CS1, LEU3_RHOPB;  Q2RV53, LEU3_RHORT;  Q3IZJ3, LEU3_RHOS4;  
Q5LWZ5, LEU3_RUEPO;  Q21IY5, LEU3_SACD2;  A4FMQ2, LEU3_SACEN;  
Q96WT9, LEU3_SACEX;  Q57TE7, LEU3_SALCH;  Q5PDG2, LEU3_SALPA;  
Q2S0M8, LEU3_SALRD;  Q8Z9I1, LEU3_SALTI;  P37412, LEU3_SALTY;  
P18869, LEU3_SCHPO;  Q8E9N3, LEU3_SHEON;  Q326G2, LEU3_SHIBS;  
Q32K21, LEU3_SHIDS;  Q83SP1, LEU3_SHIFL;  Q3Z5T7, LEU3_SHISS;  
Q2NVW4, LEU3_SODGM;  P29696, LEU3_SOLTU;  Q6TWC4, LEU3_SORMA;  
Q2FF66, LEU3_STAA3;  Q2FWK2, LEU3_STAA8;  Q2YUF1, LEU3_STAAB;  
Q5HEE3, LEU3_STAAC;  P65100, LEU3_STAAM;  P65101, LEU3_STAAN;  
Q6GF15, LEU3_STAAR;  Q6G7Q0, LEU3_STAAS;  Q8NVJ0, LEU3_STAAW;  
Q5HMF8, LEU3_STAEQ;  Q8CNL2, LEU3_STAES;  Q4L7U1, LEU3_STAHJ;  
Q49Z13, LEU3_STAS1;  Q82JN6, LEU3_STRAW;  O86504, LEU3_STRCO;  
B1VZ57, LEU3_STRGG;  Q8DTG3, LEU3_STRMU;  Q8DPJ4, LEU3_STRR6;  
Q5LZF3, LEU3_STRT1;  Q5M405, LEU3_STRT2;  Q30RK2, LEU3_SULDN;  
Q9UXB2, LEU3_SULSO;  P50455, LEU3_SULTO;  Q67JY2, LEU3_SYMTH;  
Q31N34, LEU3_SYNE7;  Q2JTN8, LEU3_SYNJA;  Q2JL30, LEU3_SYNJB;  
Q5MZ40, LEU3_SYNP6;  Q7U840, LEU3_SYNPX;  Q3AYS1, LEU3_SYNS9;  
Q3AIH4, LEU3_SYNSC;  P73960, LEU3_SYNY3;  P24098, LEU3_THEAQ;  
P59029, LEU3_THEEB;  Q47SB4, LEU3_THEFY;  Q9WZ26, LEU3_THEMA;  
P61494, LEU3_THET2;  Q5SIY4, LEU3_THET8;  P61495, LEU3_THETH;  
Q3SHL3, LEU3_THIDA;  Q9KP82, LEU3_VIBCH;  Q87SS8, LEU3_VIBPA;  
Q8DEE0, LEU3_VIBVU;  Q7MP78, LEU3_VIBVY;  Q9HDQ1, LEU3_WICAO;  
Q7M886, LEU3_WOLSU;  Q8PH05, LEU3_XANAC;  Q3BPJ8, LEU3_XANC5;  
Q4UYG2, LEU3_XANC8;  Q8P5L1, LEU3_XANCP;  Q2P762, LEU3_XANOM;  
Q5H4C7, LEU3_XANOR;  Q9PAX3, LEU3_XYLFA;  Q87BQ1, LEU3_XYLFT;  
P18120, LEU3_YARLI;  P04173, LEU3_YEAST;  Q8ZIG9, LEU3_YERPE;  
Q66EM2, LEU3_YERPS;  Q9P3Y0, LEU3_ZYGBA;  Q96WI0, LEU3_ZYGRC;  
Q5NPQ9, LEU3_ZYMMO;  Q9Y897, LEU3_ZYMTR;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-