A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.1.1.87
| Accepted Name |
|---|
| Homoisocitrate dehydrogenase.
|
| Alternative Name(s) |
|---|
| (-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD(+) oxidoreductase
(decarboxylating). |
| 2-hydroxy-3-carboxyadipate dehydrogenase. |
| 3-carboxy-2-hydroxyadipate dehydrogenase. |
| 3-carboxy-2-hydroxyadipate:NAD(+) oxidoreductase (decarboxylating). |
| Homoisocitric dehydrogenase. |
| Reaction catalysed |
|---|
| (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD(+) <=> 2-oxoadipate + CO(2) + NADH |
| Comment(s) |
|---|
- Forms part of the lysine biosynthesis pathway in fungi.
- Formerly EC 1.1.1.155.
|
| Cross-references |
|---|
| PROSITE | PDOC00389 |
| BRENDA | 1.1.1.87 |
| EC2PDB | 1.1.1.87 |
| ExplorEnz | 1.1.1.87 |
| PRIAM enzyme-specific profiles | 1.1.1.87 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.87 |
| IUBMB Enzyme Nomenclature | 1.1.1.87 |
| IntEnz | 1.1.1.87 |
| MEDLINE | Find literature relating to 1.1.1.87 |
| MetaCyc | 1.1.1.87 |
| UniProtKB/Swiss-Prot |
|
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