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ENZYME entry: EC 1.1.1.88

Accepted Name
hydroxymethylglutaryl-CoA reductase.
Alternative Name(s)
3-hydroxy-3-methylglutaryl coenzyme A reductase.
beta-hydroxy-beta-methylglutaryl CoA-reductase.
beta-hydroxy-beta-methylglutaryl coenzyme A reductase.
HMG-CoA reductase.
hydroxymethylglutaryl coenzyme A reductase.
Reaction catalysed
(R)-mevalonate + CoA + 2 NAD(+) <=> (3S)-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADH
Cross-references
BRENDA1.1.1.88
EC2PDB1.1.1.88
ExplorEnz1.1.1.88
PRIAM enzyme-specific profiles1.1.1.88
KEGG Ligand Database for Enzyme Nomenclature1.1.1.88
IUBMB Enzyme Nomenclature1.1.1.88
IntEnz1.1.1.88
MEDLINEFind literature relating to 1.1.1.88
MetaCyc1.1.1.88
Rhea expert-curated reactions1.1.1.88
UniProtKB/Swiss-Prot
O51628, HMDH_BORBU;  P13702, MVAA_PSEMV;  

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