Expasy logo

ENZYME

ENZYME entry: EC 1.1.1.n4

Accepted Name
(-)-trans-carveol dehydrogenase
Alternative Name(s)
(4R,6S)-carveol dehydrogenase
carveol dehydrogenase
CDH
Reaction catalysed
  • (1S,5R)-carveol + NAD(+) <=> (R)-carvone + H(+) + NADH
  • (1S,5S)-carveol + NAD(+) <=> (S)-carvone + H(+) + NADH
Comment(s)
  • Catalyzes the oxidation of carveol to carvone, with a strong stereoselectivity since it efficiently converts only the (6S)- stereoisomers, of which (-)-(4R,6S)-trans-carveol is the better substrate.
  • Displays a broad substrate specificity with a preference for substituted cyclohexanols, and does not catalyze the oxidation of primary or short chain aliphatic secondary alcohols.
  • Is also able, albeit more slowly, to oxidize limonene-1,2-diol into 1-hydroxy-2-oxolimonene.
Cross-references
UniProtKB/Swiss-Prot
Q9RA05, LIMC_RHOER

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-