ENZYME entry: EC 1.1.1.n4
Accepted Name |
(-)-trans-carveol dehydrogenase.
|
Alternative Name(s) |
(4R,6S)-carveol dehydrogenase. |
Carveol dehydrogenase. |
CDH. |
Reaction catalysed |
- (-)-(4R,6S)-trans-carveol + NAD(+) <=> (-)-(4R)-carvone + NADH
- (+)-(4S,6S)-cis-carveol + NAD(+) <=> (+)-(4S)-carvone + NADH
|
Comment(s) |
- Catalyzes the oxidation of carveol to carvone, with a strong
stereoselectivity since it efficiently converts only the (6S)-
stereoisomers, of which (-)-(4R,6S)-trans-carveol is the better
substrate.
- Displays a broad substrate specificity with a preference for
substituted cyclohexanols, and does not catalyze the oxidation of
primary or short chain aliphatic secondary alcohols.
- Is also able, albeit more slowly, to oxidize limonene-1,2-diol into
1-hydroxy-2-oxolimonene.
|
Cross-references |
UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-