ID   1.1.2.7
DE   methanol dehydrogenase (cytochrome c).
AN   MDH.
AN   methanol dehydrogenase.
CA   a primary alcohol + 2 Fe(III)-[cytochrome cL] = an aldehyde + 2 Fe(II)-
CA   [cytochrome cL] + 2 H(+).
CC   -!- A periplasmic quinoprotein alcohol dehydrogenase that only occurs in
CC       methylotrophic bacteria.
CC   -!- It uses the novel specific cytochrome cL as acceptor.
CC   -!- Acts on a wide range of primary alcohols, including ethanol,
CC       duodecanol, chloroethanol, cinnamyl alcohol, and also formaldehyde.
CC   -!- Activity is stimulated by ammonia or methylamine.
CC   -!- It is usually assayed with phenazine methosulfate.
CC   -!- Like all other quinoprotein alcohol dehydrogenases it has an 8-bladed
CC       'propeller' structure, a calcium ion bound to the PQQ in the active
CC       site and an unusual disulfide ring structure in close proximity to
CC       the PQQ.
CC   -!- It differs from EC 1.1.2.8, alcohol dehydrogenase (cytochrome c),
CC       in having a high affinity for methanol and in having a second
CC       essential small subunit (no known function).
CC   -!- Formerly EC 1.1.99.8.
DR   P16027, DHM1_METEA ;  P38539, DHM1_METME ;  P15279, DHM1_METOR ;
DR   P12293, DHM1_PARDE ;  P14775, DHM2_METEA ;  P38540, DHM2_METME ;
DR   Q09053, DHM2_METSP ;  P29898, DHM2_PARDE ;
//