ENZYME entry: EC 1.1.3.15
Accepted Name |
(S)-2-hydroxy-acid oxidase.
|
Alternative Name(s) |
Glycolate oxidase. |
Hydroxy-acid oxidase A. |
Hydroxy-acid oxidase B. |
Reaction catalysed |
(S)-2-hydroxy acid + O(2) <=> 2-oxo acid + H(2)O(2) |
Cofactor(s) |
FMN.
|
Comment(s) |
- Exists as two major isoenzymes; the A form preferentially oxidizes
short-chain aliphatic hydroxy acids; the B form preferentially
oxidizes long-chain and aromatic hydroxy acids.
- The rat isoenzyme B also acts as EC 1.4.3.2.
- Formerly EC 1.1.3.1.
|
Cross-references |
PROSITE | PDOC00482 |
BRENDA | 1.1.3.15 |
EC2PDB | 1.1.3.15 |
ExplorEnz | 1.1.3.15 |
PRIAM enzyme-specific profiles | 1.1.3.15 |
KEGG Ligand Database for Enzyme Nomenclature | 1.1.3.15 |
IUBMB Enzyme Nomenclature | 1.1.3.15 |
IntEnz | 1.1.3.15 |
MEDLINE | Find literature relating to 1.1.3.15 |
MetaCyc | 1.1.3.15 |
Rhea expert-curated reactions | 1.1.3.15 |
UniProtKB/Swiss-Prot |
Q9LRR9, GLO1_ARATH; | B8AKX6, GLO1_ORYSI; | Q10CE4, GLO1_ORYSJ; |
Q9LRS0, GLO2_ARATH; | Q01KC2, GLO2_ORYSI; | Q7XPR4, GLO2_ORYSJ; |
B8AUI3, GLO3_ORYSI; | Q7FAS1, GLO3_ORYSJ; | O49506, GLO5_ARATH; |
B8B7C5, GLO5_ORYSI; | Q6YT73, GLO5_ORYSJ; | A0A3L6E0R4, GOX1_MAIZE; |
P05414, GOX_SPIOL; | Q9LJH5, HAOX1_ARATH; | Q9UJM8, HAOX1_HUMAN; |
Q9WU19, HAOX1_MOUSE; | B0BNF9, HAOX1_RAT; | Q24JJ8, HAOX2_ARATH; |
Q3ZBW2, HAOX2_BOVIN; | Q9NYQ3, HAOX2_HUMAN; | Q9NYQ2, HAOX2_MOUSE; |
Q07523, HAOX2_RAT; | Q54E41, HAOX_DICDI; | B8B8K5, HAOX_ORYSI; |
Q8H3I4, HAOX_ORYSJ; | F4G5A4, LOX_ALIDK; | A0A5N1I561, LOX_LACJE; |
B1HZY7, LOX_LYSSC; | B7RR92, LOX_ROSS0; |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.1.3.-
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