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ENZYME

ENZYME entry: EC 1.1.3.15

Accepted Name
(S)-2-hydroxy-acid oxidase
Alternative Name(s)
glycolate oxidase
hydroxy-acid oxidase A
hydroxy-acid oxidase B
Reaction catalysed
a (2S)-2-hydroxycarboxylate + O2 = a 2-oxocarboxylate + H2O2
Comment(s)
  • Exists as two major isoenzymes; the A form preferentially oxidizes short-chain aliphatic hydroxy acids; the B form preferentially oxidizes long-chain and aromatic hydroxy acids.
  • The rat isoenzyme B also acts as EC 1.4.3.2.
  • Formerly EC 1.1.3.1.
Cross-references
BRENDA1.1.3.15
EC2PDB1.1.3.15
ExplorEnz1.1.3.15
PRIAM enzyme-specific profiles1.1.3.15
KEGG Ligand Database for Enzyme Nomenclature1.1.3.15
IUBMB Enzyme Nomenclature1.1.3.15
IntEnz1.1.3.15
MEDLINEFind literature relating to 1.1.3.15
MetaCyc1.1.3.15
Rhea expert-curated reactions1.1.3.15
UniProtKB/Swiss-Prot
Q9LRR9, GLO1_ARATHB8AKX6, GLO1_ORYSIQ10CE4, GLO1_ORYSJ
Q9LRS0, GLO2_ARATHQ01KC2, GLO2_ORYSIQ7XPR4, GLO2_ORYSJ
B8AUI3, GLO3_ORYSIQ7FAS1, GLO3_ORYSJO49506, GLO5_ARATH
B8B7C5, GLO5_ORYSIQ6YT73, GLO5_ORYSJA0A3L6E0R4, GOX1_MAIZE
P05414, GOX_SPIOLQ9LJH5, HAOX1_ARATHQ9UJM8, HAOX1_HUMAN
Q9WU19, HAOX1_MOUSEB0BNF9, HAOX1_RATQ24JJ8, HAOX2_ARATH
Q3ZBW2, HAOX2_BOVINQ9NYQ3, HAOX2_HUMANQ9NYQ2, HAOX2_MOUSE
Q07523, HAOX2_RATQ54E41, HAOX_DICDIB8B8K5, HAOX_ORYSI
Q8H3I4, HAOX_ORYSJF4G5A4, LOX_ALIDKA0A5N1I561, LOX_LACJE
B1HZY7, LOX_LYSSCB7RR92, LOX_ROSS0

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
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