ENZYME entry: EC 1.1.3.39
| Accepted Name |
|---|
| Nucleoside oxidase (H(2)O(2)-forming).
|
| Reaction catalysed |
|---|
| Adenosine + 2 O(2) + H(2)O <=> 9-riburonosyladenine + 2 H(2)O(2) |
| Cofactor(s) |
|---|
| FAD; Heme.
|
| Comment(s) |
|---|
- Other purine and pyrimidine nucleosides (as well as
2'-deoxyribonucleosides and arabinosides) are substrates, but ribose
and nucleotides are not substrates.
- The 5'-dehydro nucleoside is being released from the enzyme to serve
as substrate for the second reaction.
- Differs from EC 1.1.3.28 as it produces hydrogen peroxide rather than
water.
|
| Cross-references |
|---|
| BRENDA | 1.1.3.39 |
| EC2PDB | 1.1.3.39 |
| ExplorEnz | 1.1.3.39 |
| PRIAM enzyme-specific profiles | 1.1.3.39 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.3.39 |
| IUBMB Enzyme Nomenclature | 1.1.3.39 |
| IntEnz | 1.1.3.39 |
| MEDLINE | Find literature relating to 1.1.3.39 |
| MetaCyc | 1.1.3.39 |
| Rhea expert-curated reactions | 1.1.3.39 |
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UniProtKB/Swiss-Prot entries corresponding to 1.1.3.-
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