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ENZYME entry: EC 1.1.3.39

Accepted Name
Nucleoside oxidase (H(2)O(2)-forming).
Reaction catalysed
Adenosine + 2 O(2) + H(2)O <=> 9-riburonosyladenine + 2 H(2)O(2)
Cofactor(s)
FAD; Heme.
Comment(s)
  • Other purine and pyrimidine nucleosides (as well as 2'-deoxyribonucleosides and arabinosides) are substrates, but ribose and nucleotides are not substrates.
  • The 5'-dehydro nucleoside is being released from the enzyme to serve as substrate for the second reaction.
  • Differs from EC 1.1.3.28 as it produces hydrogen peroxide rather than water.
Cross-references
BRENDA1.1.3.39
EC2PDB1.1.3.39
ExplorEnz1.1.3.39
PRIAM enzyme-specific profiles1.1.3.39
KEGG Ligand Database for Enzyme Nomenclature1.1.3.39
IUBMB Enzyme Nomenclature1.1.3.39
IntEnz1.1.3.39
MEDLINEFind literature relating to 1.1.3.39
MetaCyc1.1.3.39
Rhea expert-curated reactions1.1.3.39

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