ENZYME

A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_09. Read more about EC 7 here.

ENZYME entry: EC 1.1.3.39

Accepted Name
Nucleoside oxidase (H(2)O(2)-forming).
Reaction catalysed
Adenosine + 2 O(2) + H(2)O <=> 9-riburonosyladenine + 2 H(2)O(2)
Cofactor(s)
FAD; Heme.
Comment(s)
Other purine and pyrimidine nucleosides (as well as 2'-deoxyribonucleosides and arabinosides) are substrates, but ribose and nucleotides are not substrates. The 5'-dehydro nucleoside is being released from the enzyme to serve as substrate for the second reaction. Differs from EC 1.1.3.28 as it produces hydrogen peroxide rather than water.
Cross-references
BRENDA	1.1.3.39
EC2PDB	1.1.3.39
ExplorEnz	1.1.3.39
PRIAM enzyme-specific profiles	1.1.3.39
KEGG Ligand Database for Enzyme Nomenclature	1.1.3.39
IUBMB Enzyme Nomenclature	1.1.3.39
IntEnz	1.1.3.39
MEDLINE	Find literature relating to 1.1.3.39
MetaCyc	1.1.3.39

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