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ENZYME entry: EC 1.1.5.10

Accepted Name
D-2-hydroxyacid dehydrogenase (quinone).
Alternative Name(s)
(R)-2-hydroxy acid dehydrogenase.
D-lactate dehydrogenase.
Reaction catalysed
a (2R)-2-hydroxycarboxylate + a quinone <=> a 2-oxocarboxylate + a quinol
Comment(s)
  • (R)-lactate, (R)-malate and meso-tartrate are good substrates.
  • Ubiquinone-1 and the dye 2,6-dichloroindophenol can act as acceptors; NAD(+) and NADP(+) are not acceptors.
Cross-references
BRENDA1.1.5.10
EC2PDB1.1.5.10
ExplorEnz1.1.5.10
PRIAM enzyme-specific profiles1.1.5.10
KEGG Ligand Database for Enzyme Nomenclature1.1.5.10
IUBMB Enzyme Nomenclature1.1.5.10
IntEnz1.1.5.10
MEDLINEFind literature relating to 1.1.5.10
MetaCyc1.1.5.10
Rhea expert-curated reactions1.1.5.10

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.5.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-