ENZYME entry: EC 1.1.99.27
| Accepted Name |
|---|
| (R)-pantolactone dehydrogenase (flavin).
|
| Alternative Name(s) |
|---|
| (R)-pantoyllactone dehydrogenase (flavin). |
| 2-dehydropantolactone reductase (flavin). |
| 2-dehydropantoyl-lactone reductase (flavin). |
| Reaction catalysed |
|---|
| (R)-pantolactone + acceptor <=> 2-dehydropantolactone + reduced acceptor |
| Cofactor(s) |
|---|
| FMN.
|
| Comment(s) |
|---|
- High specificity for (R)-pantolactone.
- Phenazine methosulfate (PMS) can act as acceptor.
- The enzyme has been studied in Nocardia asteroides and shown to be
membrane-bound and induced by 1,2-propanediol.
|
| Cross-references |
|---|
| BRENDA | 1.1.99.27 |
| EC2PDB | 1.1.99.27 |
| ExplorEnz | 1.1.99.27 |
| PRIAM enzyme-specific profiles | 1.1.99.27 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.99.27 |
| IUBMB Enzyme Nomenclature | 1.1.99.27 |
| IntEnz | 1.1.99.27 |
| MEDLINE | Find literature relating to 1.1.99.27 |
| MetaCyc | 1.1.99.27 |
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