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ENZYME entry: EC 1.1.99.27

Accepted Name
(R)-pantolactone dehydrogenase (flavin).
Alternative Name(s)
(R)-pantoyllactone dehydrogenase (flavin).
2-dehydropantolactone reductase (flavin).
2-dehydropantoyl-lactone reductase (flavin).
Reaction catalysed
(R)-pantolactone + acceptor <=> 2-dehydropantolactone + reduced acceptor
Cofactor(s)
FMN.
Comment(s)
  • High specificity for (R)-pantolactone.
  • Phenazine methosulfate (PMS) can act as acceptor.
  • The enzyme has been studied in Nocardia asteroides and shown to be membrane-bound and induced by 1,2-propanediol.
Cross-references
BRENDA1.1.99.27
EC2PDB1.1.99.27
ExplorEnz1.1.99.27
PRIAM enzyme-specific profiles1.1.99.27
KEGG Ligand Database for Enzyme Nomenclature1.1.99.27
IUBMB Enzyme Nomenclature1.1.99.27
IntEnz1.1.99.27
MEDLINEFind literature relating to 1.1.99.27
MetaCyc1.1.99.27
Rhea expert-curated reactions1.1.99.27

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