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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
Pyranose dehydrogenase (acceptor).
Alternative Name(s)
Pyranose dehydrogenase.
Pyranose-quinone oxidoreductase.
Quinone-dependent pyranose dehydrogenase.
Reaction catalysed
  • Pyranose + acceptor <=> pyranos-2-ulose + reduced acceptor
  • Pyranose + acceptor <=> pyranos-3-ulose + reduced acceptor
  • Pyranose + acceptor <=> pyranos-2,3-diulose + reduced acceptor
  • A pyranoside + acceptor <=> a pyranosid-3-ulose + reduced acceptor
  • A pyranoside + acceptor <=> a pyranosid-3,4-diulose + reduced acceptor
  • A number of aldoses and ketoses in pyranose form, as well as glycosides, gluco-oligosaccharides, sucrose and lactose can act as a donor.
  • 1,4-benzoquinone or ferricenium ion (ferrocene oxidized by removal of one electron) can serve as acceptor.
  • Unlike EC, this fungal enzyme does not interact with O(2) and exhibits extremely broad substrate tolerance with variable regioselectivity (C-3, C-2 or C-3 + C-2 or C-3 + C-4) for (di)oxidation of different sugars.
  • D-glucose is exclusively or preferentially oxidized at C-3 (depending on the enzyme source), but can also be oxidized at C-2 + C-3.
  • The enzyme also acts on 1->4-alpha- and 1->4-beta-gluco- oligosaccharides, non-reducing gluco-oligosaccharides and L-arabinose, which are not substrates of EC
  • Sugars are oxidized in their pyranose but not in their furanose form.
PRIAM enzyme-specific profiles1.1.99.29
KEGG Ligand Database for Enzyme Nomenclature1.1.99.29
IUBMB Enzyme Nomenclature1.1.99.29
MEDLINEFind literature relating to
Q3L245, PDH1_LEUMG;  Q3L243, PDH2_LEUMG;  Q0R4L2, PDH3_LEUMG;  

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