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ENZYME entry: EC 1.1.99.30
Accepted Name |
2-oxo-acid reductase.
|
Alternative Name(s) |
(2R)-hydroxycarboxylate-viologen-oxidoreductase. |
2-oxoacid reductase. |
HVOR. |
Reaction catalysed |
A + a (2R)-2-hydroxycarboxylate <=> a 2-oxocarboxylate + AH2 |
Comment(s) |
- Has broad substrate specificity, with 2-oxo-monocarboxylates and
2-oxo-dicarboxylates acting as substrates.
- Branching in a substrate at the C-3 position results in loss of
activity.
- The enzyme from Proteus sp. is inactivated by oxygen.
|
Cross-references |
BRENDA | 1.1.99.30 |
EC2PDB | 1.1.99.30 |
ExplorEnz | 1.1.99.30 |
PRIAM enzyme-specific profiles | 1.1.99.30 |
KEGG Ligand Database for Enzyme Nomenclature | 1.1.99.30 |
IUBMB Enzyme Nomenclature | 1.1.99.30 |
IntEnz | 1.1.99.30 |
MEDLINE | Find literature relating to 1.1.99.30 |
MetaCyc | 1.1.99.30 |
Rhea expert-curated reactions | 1.1.99.30 |
UniProtKB/Swiss-Prot |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.1.99.-
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