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ENZYME

ENZYME entry: EC 1.1.99.30

PURL: https://purl.expasy.org/enzyme/EC/1.1.99.30
Accepted Name
2-oxo-acid reductase
Alternative Name(s)
(2R)-hydroxycarboxylate-viologen-oxidoreductase
2-oxoacid reductase
HVOR
Reaction catalysed
a (2R)-2-hydroxycarboxylate + A = a 2-oxocarboxylate + AH2
Comment(s)
  • Has broad substrate specificity, with 2-oxo-monocarboxylates and 2-oxo-dicarboxylates acting as substrates.
  • Branching in a substrate at the C-3 position results in loss of activity.
  • The enzyme from Proteus sp. is inactivated by oxygen.
Cross-references
BRENDA1.1.99.30
EC2PDB1.1.99.30
ExplorEnz1.1.99.30
KEGG Ligand Database for Enzyme Nomenclature1.1.99.30
IUBMB Enzyme Nomenclature1.1.99.30
MEDLINEFind literature relating to 1.1.99.30
MetaCyc1.1.99.30
Rhea expert-curated reactions1.1.99.30
UniProtKB/Swiss-Prot
Q9R4Y1, HVOR_PROHU

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