ID 1.1.99.39 DE D-2-hydroxyglutarate dehydrogenase. CA (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor. CF FAD. CC -!- The enzyme has no activity with NAD(+) or NADP(+), and was assayed in CC vitro using artificial electron acceptors. CC -!- It has lower activity with (R)-lactate, (R)-2-hydroxybutyrate and CC meso-tartrate, and no activity with the (S) isomers. DR O23240, D2HDH_ARATH; Q1JPD3, D2HDH_BOVIN; A1L258, D2HDH_DANRE; DR Q8N465, D2HDH_HUMAN; Q8CIM3, D2HDH_MOUSE; B8B7X6, D2HDH_ORYSI; DR Q7XI14, D2HDH_ORYSJ; A4VGK4, D2HDH_PSEU5; P84850, D2HDH_RAT ; DR P0DV35, D2HDH_XANCL; //