ENZYME entry: EC 1.1.99.40

Accepted Name
(R)-2-hydroxyglutarate--pyruvate transhydrogenase.
Reaction catalysed
(R)-2-hydroxyglutarate + pyruvate <=> 2-oxoglutarate + (R)-lactate
Comment(s)
The enzyme, characterized in the yeast Saccharomyces cerevisiae, also functions as EC 1.1.2.4 and is active with oxaloacetate as electron acceptor forming (R)-malate.
Cross-references
BRENDA1.1.99.40
EC2PDB1.1.99.40
ExplorEnz1.1.99.40
PRIAM enzyme-specific profiles1.1.99.40
KEGG Ligand Database for Enzyme Nomenclature1.1.99.40
IUBMB Enzyme Nomenclature1.1.99.40
IntEnz1.1.99.40
MEDLINEFind literature relating to 1.1.99.40
MetaCyc1.1.99.40
UniProtKB/Swiss-Prot
P46681, DLD2_YEAST;  P39976, DLD3_YEAST;  

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