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ENZYME entry: EC 1.1.99.6

Accepted Name
D-lactate dehydrogenase (acceptor).
Reaction catalysed
(R)-lactate + acceptor <=> pyruvate + reduced acceptor
Cofactor(s)
FAD; Zn(2+).
Comment(s)
  • The enzyme from the archaeon Archaeoglobus fulgidus cannot utilize NAD(+), cytochrome C, methylene blue or dimethylnaphthoquinone as acceptors.
  • In vitro it is active with artificial electron acceptors such as 2,6- dichlorophenolindophenol, but the physiological acceptor is not yet known.
Cross-references
BRENDA1.1.99.6
EC2PDB1.1.99.6
ExplorEnz1.1.99.6
PRIAM enzyme-specific profiles1.1.99.6
KEGG Ligand Database for Enzyme Nomenclature1.1.99.6
IUBMB Enzyme Nomenclature1.1.99.6
IntEnz1.1.99.6
MEDLINEFind literature relating to 1.1.99.6
MetaCyc1.1.99.6
UniProtKB/Swiss-Prot
O29853, DLD_ARCFU

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