Expasy logo

ENZYME

ENZYME entry: EC 1.10.3.15

PURL: https://purl.expasy.org/enzyme/EC/1.10.3.15
Accepted Name
grixazone synthase
Reaction catalysed
2 3-amino-4-hydroxybenzoate + N-acetyl-L-cysteine + 2 O2 + H(+) = grixazone B + CO2 + 4 H2O
Comment(s)
  • The enzyme, isolated from the bacterium Streptomyces griseus, catalyzes an 8 electron oxidation.
  • Activation of the enzyme requires a copper chaperone (GriE).
  • It also acts on 3-amino-4-hydroxybenzaldehyde, giving grixazone A.
  • The second aldehyde group is presumably lost as formate.
  • The enzyme also catalyzes the reaction of EC 1.10.3.4.
Cross-references
BRENDA1.10.3.15
EC2PDB1.10.3.15
ExplorEnz1.10.3.15
KEGG Ligand Database for Enzyme Nomenclature1.10.3.15
IUBMB Enzyme Nomenclature1.10.3.15
MEDLINEFind literature relating to 1.10.3.15
MetaCyc1.10.3.15
Rhea expert-curated reactions1.10.3.15
UniProtKB/Swiss-Prot
B1VTI5, GRIF_STRGG

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.10.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.10.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-