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ENZYME

ENZYME entry: EC 1.10.3.16

PURL: https://purl.expasy.org/enzyme/EC/1.10.3.16
Accepted Name
dihydrophenazinedicarboxylate synthase
Reaction catalysed
  • (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + O2 = (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate + H2O2
  • (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate + O2 = (5aS)-5,5a-dihydrophenazine-1,6-dicarboxylate + H2O2
  • (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + O2 = (10aS)-10,10a-dihydrophenazine-1-carboxylate + H2O2
  • (1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate + O2 = (10aS)-10,10a-dihydrophenazine-1-carboxylate + H2O2
Comment(s)
The enzyme, isolated from the bacteria Pseudomonas fluorescens 2-79 and Burkholderia lata 383, is involved in biosynthesis of the reduced forms of phenazine, phenazine-1-carboxylate, and phenazine-1,6- dicarboxylate, where it catalyzes multiple reactions.
Cross-references
BRENDA1.10.3.16
EC2PDB1.10.3.16
ExplorEnz1.10.3.16
KEGG Ligand Database for Enzyme Nomenclature1.10.3.16
IUBMB Enzyme Nomenclature1.10.3.16
MEDLINEFind literature relating to 1.10.3.16
MetaCyc1.10.3.16
Rhea expert-curated reactions1.10.3.16
UniProtKB/Swiss-Prot
Q51521, PHZD_PSECLQ396C5, PHZG_BURL3Q51793, PHZG_PSEFL

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