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ENZYME entry: EC 1.11.1.7

Accepted Name
Peroxidase.
Alternative Name(s)
Lactoperoxidase.
Reaction catalysed
2 phenolic donor + H(2)O(2) <=> 2 phenoxyl radical of the donor + 2 H(2)O
Cofactor(s)
Heme.
Comment(s)
  • Heme proteins with histidine as proximal ligand.
  • The iron in the resting enzyme is Fe(III).
  • They also peroxidize non-phenolic substrates such as 3,3',5,5'-tetramethylbenzidine (TMB) and 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS).
  • Certain peroxidases (e.g. lactoperoxidase, SBP) oxidize bromide, iodide and thiocyanate.
Cross-references
PROSITEPDOC00394
BRENDA1.11.1.7
EC2PDB1.11.1.7
ExplorEnz1.11.1.7
PRIAM enzyme-specific profiles1.11.1.7
KEGG Ligand Database for Enzyme Nomenclature1.11.1.7
IUBMB Enzyme Nomenclature1.11.1.7
IntEnz1.11.1.7
MEDLINEFind literature relating to 1.11.1.7
MetaCyc1.11.1.7
Rhea expert-curated reactions1.11.1.7
UniProtKB/Swiss-Prot
Q55080, CP119_SULAC;  K7N5M8, DYP2_AMYS7;  I2DBY1, DYP_AURAJ;  
I2DBY2, DYP_EXIGL;  I2DBY3, DYP_MYCEP;  P90820, HPX2_CAEEL;  
C0IW58, LNP_TAICA;  Q23490, MLT7_CAEEL;  B0BK71, MSP1_MYCSO;  
Q9FX85, PER10_ARATH;  P86067, PER10_DAUCA;  Q96519, PER11_ARATH;  
Q96520, PER12_ARATH;  O49293, PER13_ARATH;  Q9SI17, PER14_ARATH;  
Q9SI16, PER15_ARATH;  Q9LEH3, PER15_IPOBA;  Q96518, PER16_ARATH;  
Q9SJZ2, PER17_ARATH;  Q9SK52, PER18_ARATH;  O22959, PER19_ARATH;  
P00433, PER1A_ARMRU;  P15232, PER1B_ARMRU;  P15233, PER1C_ARMRU;  
P22195, PER1_ARAHY;  P0DI10, PER1_ARATH;  P85331, PER1_BETPN;  
P85999, PER1_CAPAN;  P85439, PER1_CATRO;  P85346, PER1_CYCRE;  
P86054, PER1_DAUCA;  P27337, PER1_HORVU;  A5H8G4, PER1_MAIZE;  
P37834, PER1_ORYSJ;  P15003, PER1_SOLLC;  P84516, PER1_SORBI;  
P86103, PER1_VITRO;  P86014, PER1_VITVI;  Q05855, PER1_WHEAT;  
Q4W1I8, PER1_ZINVI;  Q9SLH7, PER20_ARATH;  Q42580, PER21_ARATH;  
P24102, PER22_ARATH;  O80912, PER23_ARATH;  Q9ZV04, PER24_ARATH;  
O80822, PER25_ARATH;  O22862, PER26_ARATH;  Q43735, PER27_ARATH;  
Q9SS67, PER28_ARATH;  Q9LSP0, PER29_ARATH;  P22196, PER2_ARAHY;  
Q67Z07, PER2_ARATH;  P17179, PER2_ARMRU;  P85333, PER2_BETPN;  
P86000, PER2_CAPAN;  P19135, PER2_CUCSA;  P85347, PER2_CYCRE;  
P86055, PER2_DAUCA;  Q01548, PER2_HORVU;  Q9FEQ8, PER2_MAIZE;  
A2YPX3, PER2_ORYSI;  Q0D3N0, PER2_ORYSJ;  P15004, PER2_SOLLC;  
P85994, PER2_VITVI;  Q4W1I9, PER2_ZINVI;  Q9LSY7, PER30_ARATH;  
Q9LHA7, PER31_ARATH;  Q9LHB9, PER32_ARATH;  P24101, PER33_ARATH;  
Q9SMU8, PER34_ARATH;  Q96510, PER35_ARATH;  Q9SD46, PER36_ARATH;  
Q9LDN9, PER37_ARATH;  Q9LDA4, PER38_ARATH;  Q9SUT2, PER39_ARATH;  
O23044, PER3_ARATH;  P17180, PER3_ARMRU;  P85334, PER3_BETPN;  
P86001, PER3_CAPAN;  P85348, PER3_CYCRE;  P86056, PER3_DAUCA;  
P85996, PER3_SOLLC;  P86015, PER3_VITVI;  O23474, PER40_ARATH;  
O23609, PER41_ARATH;  Q9SB81, PER42_ARATH;  A5H453, PER42_MAIZE;  
Q9SZH2, PER43_ARATH;  Q93V93, PER44_ARATH;  Q96522, PER45_ARATH;  
O81772, PER46_ARATH;  Q9SZB9, PER47_ARATH;  O81755, PER48_ARATH;  
O23237, PER49_ARATH;  Q9LE15, PER4_ARATH;  P85335, PER4_BETPN;  
P86002, PER4_CAPAN;  P85349, PER4_CYCRE;  P86057, PER4_DAUCA;  
P85998, PER4_SOLLC;  A7NY33, PER4_VITVI;  Q43731, PER50_ARATH;  
Q9SZE7, PER51_ARATH;  Q9FLC0, PER52_ARATH;  Q42578, PER53_ARATH;  
Q9FG34, PER54_ARATH;  Q96509, PER55_ARATH;  Q9LXG3, PER56_ARATH;  
Q43729, PER57_ARATH;  P59120, PER58_ARATH;  Q39034, PER59_ARATH;  
Q9M9Q9, PER5_ARATH;  P85351, PER5_BETPN;  P86003, PER5_CAPAN;  
P85431, PER5_CYCRE;  P86058, PER5_DAUCA;  A7QEU4, PER5_VITVI;  
Q9FMR0, PER60_ARATH;  Q9FLV5, PER61_ARATH;  Q9FKA4, PER62_ARATH;  
Q9FL16, PER63_ARATH;  Q43872, PER64_ARATH;  Q9FJR1, PER65_ARATH;  
Q9LT91, PER66_ARATH;  A5H454, PER66_MAIZE;  Q9LVL2, PER67_ARATH;  
Q9LVL1, PER68_ARATH;  Q96511, PER69_ARATH;  O48677, PER6_ARATH;  
P86004, PER6_CAPAN;  P85432, PER6_CYCRE;  P86062, PER6_DAUCA;  
P85995, PER6_VITVI;  Q9FMI7, PER70_ARATH;  A5H452, PER70_MAIZE;  
Q43387, PER71_ARATH;  Q9FJZ9, PER72_ARATH;  Q43873, PER73_ARATH;  
Q9SY33, PER7_ARATH;  P86006, PER7_CAPAN;  P85433, PER7_CYCRE;  
P86063, PER7_DAUCA;  Q9LNL0, PER8_ARATH;  P86007, PER8_CAPAN;  
P85434, PER8_CYCRE;  P86064, PER8_DAUCA;  Q96512, PER9_ARATH;  
P86008, PER9_CAPAN;  P85976, PER9_CYCRE;  P86066, PER9_DAUCA;  
P80679, PERA2_ARMRU;  P84752, PERA_ALOVR;  O04795, PERA_IPOBA;  
P84753, PERB_ALOVR;  P82600, PERC_AEDAE;  Q7QH73, PERC_ANOGA;  
P85332, PERC_BETPN;  Q9VEG6, PERC_DROME;  P59121, PERE5_ARMRU;  
P11678, PERE_HUMAN;  P49290, PERE_MOUSE;  P80550, PERE_PIG;  
P80025, PERL_BOVIN;  A5JUY8, PERL_BUBBU;  A0A452E9Y6, PERL_CAPHI;  
P22079, PERL_HUMAN;  Q8R481, PERL_MESAU;  Q9XIV8, PERN1_TOBAC;  
Q42517, PERN_ARMRU;  O04796, PERN_IPOBA;  Q01603, PERO_DROME;  
B3EWG7, PERO_PLEPU;  P00434, PERP7_BRARR;  P16147, PERX_LUPPO;  
Q02200, PERX_NICSY;  P12437, PERX_SOLTU;  P11965, PERX_TOBAC;  
P15984, PERX_WHEAT;  P28313, PER_ARTRA;  A8NK72, PER_COPC7;  
P28314, PER_COPCI;  P84714, PER_CYNCS;  P85317, PER_GINBI;  
P85957, PER_PSEMZ;  Q6TMK4, POXA_DICDI;  Q9SCX8, PPA17_ARATH;  
Q949Y3, PPA26_ARATH;  A8WQH2, PXDN1_CAEBR;  Q1ENI8, PXDN1_CAEEL;  
G5EG78, PXDN2_CAEEL;  A1KZ92, PXDNL_HUMAN;  Q9VZZ4, PXDN_DROME;  
Q92626, PXDN_HUMAN;  Q3UQ28, PXDN_MOUSE;  A4IGL7, PXDN_XENTR;  
Q20616, SKPO1_CAEEL;  

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