ID   1.11.2.1
DE   Unspecific peroxygenase.
AN   Haloperoxidase-peroxygenase.
CA   RH + H(2)O(2) = ROH + H(2)O.
CF   Heme-thiolate.
CC   -!- Enzymes of this type include glycoproteins secreted by agaric
CC       basidiomycetes.
CC   -!- They catalyze the insertion of an oxygen atom from H(2)O(2) into a
CC       wide variety of substrates, including aromatic rings such as
CC       naphthalene, toluene, phenanthrene, pyrene and p-nitrophenol,
CC       recalcitrant heterocycles such as pyridine, dibenzofuran, various
CC       ethers (resulting in O-dealkylation) and alkanes such as propane,
CC       hexane and cyclohexane.
CC   -!- Reactions catalyzed include hydroxylation, epoxidation, N-oxidation,
CC       sulfooxidation, O- and N-dealkylation, bromination and one-electron
CC       oxidations.
CC   -!- They have little or no activity toward chloride.
CC   -!- Mechanistically, the catalytic cycle of unspecific (mono)-
CC       peroxygenases combines elements of the 'shunt' pathway of cytochrome
CC       P450s (a side activity that utilizes a peroxide in place of dioxygen
CC       and NAD(P)H) and the classic heme peroxidase cycle.
PR   PROSITE; PDOC00394;
DR   B9W4V6, APO1_AGRAE ;
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