ID   1.11.2.4
DE   fatty-acid peroxygenase.
AN   CYP152A1.
AN   fatty acid hydroxylase.
AN   P450 peroxygenase.
AN   P450SPalpha.
CA   (1) a 1,2-saturated fatty acid + H2O2 = a 2-hydroxy fatty acid + H2O.
CA   (2) a 2,3-saturated fatty acid + H2O2 = a 3-hydroxy fatty acid + H2O.
CC   -!- A cytosolic heme-thiolate protein with sequence homology to P450
CC       monooxygenases.
CC   -!- Unlike the latter, it needs neither NAD(P)H, dioxygen nor specific
CC       reductases for function.
CC   -!- Enzymes of this type are produced by bacteria (e.g. Sphingomonas
CC       paucimobilis, Bacillus subtilis).
CC   -!- Catalytic turnover rates are high compared with those of
CC       monooxygenation reactions as well as peroxide shunt reactions
CC       catalyzed by the common P450s.
CC   -!- A model substrate is myristate, but other saturated and unsaturated
CC       fatty acids are also hydroxylated.
CC   -!- Oxidizes the peroxidase substrate 3,3,5,5-tetramethylbenzidine (TMB)
CC       and peroxygenates aromatic substrates in a fatty-acid-dependent
CC       reaction.
DR   I3DZK9, CYPC_BACMM ;  O31440, CYPC_BACSU ;
//