ID 1.12.1.3 DE hydrogen dehydrogenase (NADP(+)). AN NADP(+)-linked hydrogenase. AN NADP(+)-reducing hydrogenase. CA H2 + NADP(+) = H(+) + NADPH. CC -!- The protein from the bacterium Desulfovibrio fructosovorans CC exclusively functions as a hydrogen dehydrogenase, while the enzyme CC from the archaeon Pyrococcus furiosus is part of a heterotetrameric CC complex where the alpha and delta subunits function as a hydrogenase CC while the beta and gamma subunits function as sulfur reductase CC (EC 1.12.98.4). CC -!- Different from EC 1.12.1.5. DR Q46505, HNDA_SOLFR ; Q46506, HNDB_SOLFR ; Q46507, HNDC_SOLFR ; DR Q46508, HNDD_SOLFR ; E7FI44, HYD1A_PYRFU; E7FHU4, HYD1D_PYRFU; //