ID 1.12.1.4 DE hydrogenase (NAD(+), ferredoxin). AN bifurcating [FeFe] hydrogenase. CA 2 H2 + NAD(+) + 2 oxidized [2Fe-2S]-[ferredoxin] = 3 H(+) + NADH + CA 2 reduced [2Fe-2S]-[ferredoxin]. CC -!- The enzyme from Thermotoga maritima contains a [FeFe] cluster CC (H-cluster) and iron-sulfur clusters. CC -!- It works in the direction evolving hydrogen as a means of eliminating CC excess reducing equivalents. DR O52683, HYDA_THEMA ; O52682, HYDB_THEMA ; O52681, HYDC_THEMA ; //