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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.12.5.1

Accepted Name
Hydrogen:quinone oxidoreductase.
Alternative Name(s)
Hydrogen-ubiquinone oxidoreductase.
Hydrogen:menaquinone oxidoreductase.
Membrane-bound hydrogenase.
Quinone-reactive Ni/Fe-hydrogenase.
Reaction catalysed
H(2) + menaquinone <=> menaquinol
Cofactor(s)
Iron-sulfur; Ni(2+).
Comment(s)
  • Also catalyzes the reduction of water-soluble quinones (e.g. 2,3- dimethylnaphthoquinone) or viologen dyes (benzylviologen or methylviologen) by H(2).
  • Formerly EC 1.12.99.3.
Cross-references
PROSITEPDOC00400
BRENDA1.12.5.1
EC2PDB1.12.5.1
ExplorEnz1.12.5.1
PRIAM enzyme-specific profiles1.12.5.1
KEGG Ligand Database for Enzyme Nomenclature1.12.5.1
IUBMB Enzyme Nomenclature1.12.5.1
IntEnz1.12.5.1
MEDLINEFind literature relating to 1.12.5.1
MetaCyc1.12.5.1
UniProtKB/Swiss-Prot
P31883, MBHL_WOLSU;  P31884, MBHS_WOLSU;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.12.5.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.12.-.-
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