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ENZYME

ENZYME entry: EC 1.12.98.1

PURL: https://purl.expasy.org/enzyme/EC/1.12.98.1
Accepted Name
coenzyme F420 hydrogenase
Alternative Name(s)
8-hydroxy-5-deazaflavin-reducing hydrogenase
coenzyme F420-dependent hydrogenase
F420-reducing hydrogenase
Reaction catalysed
oxidized coenzyme F420-(gamma-L-Glu)(n) + H2 + H(+) = reduced coenzyme F420-(gamma-L-Glu)(n)
Comment(s)
  • The enzyme from some sources contains selenocysteine.
  • The enzyme also reduces the riboflavin analog of F420, flavins and methylviologen, but to a lesser extent.
  • The hydrogen acceptor coenzyme F420 is a deazaflavin derivative.
  • Formerly EC 1.12.99.1.
Cross-references
BRENDA1.12.98.1
EC2PDB1.12.98.1
ExplorEnz1.12.98.1
KEGG Ligand Database for Enzyme Nomenclature1.12.98.1
IUBMB Enzyme Nomenclature1.12.98.1
MEDLINEFind literature relating to 1.12.98.1
MetaCyc1.12.98.1
Rhea expert-curated reactions1.12.98.1
UniProtKB/Swiss-Prot
P80489, FRHA_METBFQ60338, FRHA_METJAP19496, FRHA_METTH
Q00390, FRHA_METVOP80490, FRHB_METBFQ60341, FRHB_METJA
P19499, FRHB_METTHQ00391, FRHB_METVOP80491, FRHG_METBF
Q60340, FRHG_METJAP19498, FRHG_METTHQ00393, FRHG_METVO

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