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ENZYME

ENZYME entry: EC 1.13.11.31

PURL: https://purl.expasy.org/enzyme/EC/1.13.11.31
Accepted Name
arachidonate 12-lipoxygenase
Alternative Name(s)
12-lipoxygenase
Reaction catalysed
(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
Comment(s)
The product is rapidly reduced to the corresponding 12S-hydroxy compound.
Cross-references
BRENDA1.13.11.31
EC2PDB1.13.11.31
ExplorEnz1.13.11.31
KEGG Ligand Database for Enzyme Nomenclature1.13.11.31
IUBMB Enzyme Nomenclature1.13.11.31
MEDLINEFind literature relating to 1.13.11.31
MetaCyc1.13.11.31
Rhea expert-curated reactions1.13.11.31
UniProtKB/Swiss-Prot
P18054, LOX12_HUMANP39655, LOX12_MOUSEF1LQ70, LOX12_RAT
P27479, LOX15_BOVINP16050, LOX15_HUMANP39654, LOX15_MOUSE
P16469, LOX15_PIGQ5RBE8, LOX15_PONABP12530, LOX15_RABIT
Q02759, LOX15_RATP55249, LX12E_MOUSED3ZQF9, LX12E_RAT

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