A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.13.11.33
Accepted Name |
Arachidonate 15-lipoxygenase.
|
Alternative Name(s) |
15-lipoxygenase. |
Arachidonate omega(6) lipoxygenase. |
Reaction catalysed |
Arachidonate + O(2) <=> (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate |
Cofactor(s) |
Fe cation.
|
Comment(s) |
The product is rapidly converted to the corresponding 15S-hydroxy
compound.
|
Cross-references |
PROSITE | PDOC00077 |
BRENDA | 1.13.11.33 |
EC2PDB | 1.13.11.33 |
ExplorEnz | 1.13.11.33 |
PRIAM enzyme-specific profiles | 1.13.11.33 |
KEGG Ligand Database for Enzyme Nomenclature | 1.13.11.33 |
IUBMB Enzyme Nomenclature | 1.13.11.33 |
IntEnz | 1.13.11.33 |
MEDLINE | Find literature relating to 1.13.11.33 |
MetaCyc | 1.13.11.33 |
UniProtKB/Swiss-Prot |
P27479, LOX15_BOVIN; | P16050, LOX15_HUMAN; | P39654, LOX15_MOUSE; |
P16469, LOX15_PIG; | Q5RBE8, LOX15_PONAB; | P12530, LOX15_RABIT; |
Q02759, LOX15_RAT; | Q9I4G8, LOXA_PSEAE; | O15296, LX15B_HUMAN; |
Q8K4F2, LX15B_RAT; |
|
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