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ENZYME

ENZYME entry: EC 1.13.11.47

PURL: https://purl.expasy.org/enzyme/EC/1.13.11.47
Accepted Name
3-hydroxy-4-oxoquinoline 2,4-dioxygenase
Alternative Name(s)
(1H)-3-hydroxy-4-oxoquinoline 2,4-dioxygenase
3-hydroxy-4(1H)-one, 2,4-dioxygenase
3-hydroxy-4-oxo-1,4-dihydroquinoline 2,4-dioxygenase
quinoline-3,4-diol 2,4-dioxygenase
Reaction catalysed
3-hydroxy-1H-quinolin-4-one + O2 = N-formylanthranilate + CO + H(+)
Comment(s)
  • Does not contain a metal center or organic cofactor.
  • Fission of two C-C bonds: 2,4-dioxygenolytic cleavage with concomitant release of carbon monoxide.
  • The enzyme from Pseudomonas putida is highly specific for this substrate.
  • Formerly EC 1.12.99.5 and EC 1.13.99.5.
Cross-references
BRENDA1.13.11.47
EC2PDB1.13.11.47
ExplorEnz1.13.11.47
KEGG Ligand Database for Enzyme Nomenclature1.13.11.47
IUBMB Enzyme Nomenclature1.13.11.47
MEDLINEFind literature relating to 1.13.11.47
MetaCyc1.13.11.47
Rhea expert-curated reactions1.13.11.47
UniProtKB/Swiss-Prot
O33472, QDO_PSEPU

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