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ENZYME

ENZYME entry: EC 1.13.11.64

Accepted Name
5-nitrosalicylate dioxygenase
Reaction catalysed
5-nitrosalicylate + O2 <=> 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H(+) + nitrite
Comment(s)
  • The enzyme, characterized from the soil bacterium Bradyrhizobium sp. JS329, is involved in the pathway of 5-nitroanthranilate degradation.
  • It is unusual in being able to catalyze the ring fission without the requirement for prior removal of the nitro group.
  • The product undergoes spontaneous lactonization, with concurrent elimination of the nitro group.
Cross-references
BRENDA1.13.11.64
EC2PDB1.13.11.64
ExplorEnz1.13.11.64
PRIAM enzyme-specific profiles1.13.11.64
KEGG Ligand Database for Enzyme Nomenclature1.13.11.64
IUBMB Enzyme Nomenclature1.13.11.64
IntEnz1.13.11.64
MEDLINEFind literature relating to 1.13.11.64
MetaCyc1.13.11.64
Rhea expert-curated reactions1.13.11.64
UniProtKB/Swiss-Prot
D3WZ86, NAAB_BRASZ

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