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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.13.11.66

Accepted Name
Hydroquinone 1,2-dioxygenase.
Alternative Name(s)
Hydroquinone dioxygenase.
Reaction catalysed
Benzene-1,4-diol + O(2) <=> (2E,4Z)-4-hydroxy-6-oxohexa-2,4-dienoate
Cofactor(s)
Fe cation.
Comment(s)
  • The enzyme is an extradiol-type dioxygenase, and is a member of the nonheme-iron(II)-dependent dioxygenase family.
  • It catalyzes the ring cleavage of a wide range of hydroquinone substrates to produce the corresponding 4-hydroxymuconic semialdehydes.
Cross-references
BRENDA1.13.11.66
EC2PDB1.13.11.66
ExplorEnz1.13.11.66
PRIAM enzyme-specific profiles1.13.11.66
KEGG Ligand Database for Enzyme Nomenclature1.13.11.66
IUBMB Enzyme Nomenclature1.13.11.66
IntEnz1.13.11.66
MEDLINEFind literature relating to 1.13.11.66
MetaCyc1.13.11.66
UniProtKB/Swiss-Prot
Q9WXE6, LINE_SPHJU

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