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ENZYME entry: EC 1.13.11.84

Accepted Name
Crocetin dialdehyde synthase.
Alternative Name(s)
Zeaxanthin 7,8-dioxygenase.
Reaction catalysed
Zeaxanthin + 2 O(2) <=> crocetin dialdehyde + 2 3-beta-hydroxy-beta-cyclocitral
Comment(s)
  • The enzyme, characterized from the plant Crocus sativus (saffron), acts twice, cleaving 3-beta-hydroxy-beta-cyclocitral off each 3-hydroxy end group.
  • It is part of the zeaxanthin degradation pathway in that plant, leading to the different compounds that impart the color, flavor and aroma of the saffron spice.
  • The enzyme can similarly cleave the 7-8 double bond of other carotenoids with a 3-hydroxy-beta-carotenoid end group.
  • Formerly EC 1.14.99.42 and EC 1.14.99.n3.
Cross-references
BRENDA1.13.11.84
EC2PDB1.13.11.84
ExplorEnz1.13.11.84
PRIAM enzyme-specific profiles1.13.11.84
KEGG Ligand Database for Enzyme Nomenclature1.13.11.84
IUBMB Enzyme Nomenclature1.13.11.84
IntEnz1.13.11.84
MEDLINEFind literature relating to 1.13.11.84
MetaCyc1.13.11.84
UniProtKB/Swiss-Prot
Q84K96, ZCD_CROSA

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