ENZYME entry: EC 1.13.12.15
Accepted Name |
3,4-dihydroxyphenylalanine oxidative deaminase.
|
Alternative Name(s) |
DOPA oxidative deaminase. |
DOPAODA. |
Oxidative deaminase. |
Reaction catalysed |
2 L-dopa + O(2) <=> 2 3,4-dihydroxyphenylpyruvate + 2 NH(3) |
Comment(s) |
- One of the three enzymes involved in L-dopa (3,4-
dihydroxyphenylalanine) catabolism in the non-oxygenic phototrophic
bacterium Rubrivivax benzoatilyticus OU5 (and not Rhodobacter
sphaeroides OU5 as had been thought), the other two being EC 4.3.1.22
and EC 2.6.1.49.
- In addition to DOPA, the enzyme can also use L-tyrosine,
L-phenylalanine, L-tryptophan and glutamate as substrate, but more
slowly.
- Inhibited by NADH and 2-oxoglutarate.
|
Cross-references |
BRENDA | 1.13.12.15 |
EC2PDB | 1.13.12.15 |
ExplorEnz | 1.13.12.15 |
PRIAM enzyme-specific profiles | 1.13.12.15 |
KEGG Ligand Database for Enzyme Nomenclature | 1.13.12.15 |
IUBMB Enzyme Nomenclature | 1.13.12.15 |
IntEnz | 1.13.12.15 |
MEDLINE | Find literature relating to 1.13.12.15 |
MetaCyc | 1.13.12.15 |
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