ID   1.13.12.17
DE   dichloroarcyriaflavin A synthase.
CA   dichlorochromopyrrolate + 4 NADH + 4 O2 + 6 H(+) = dichloroarcyriaflavin
CA   A + 2 CO2 + 4 NAD(+) + 6 H2O.
CC   -!- The conversion of dichlorochromopyrrolate to dichloroarcyriaflavin A
CC       is a complex process that involves two enzyme components.
CC   -!- RebP is an NAD-dependent cytochrome P450 oxygenase that performs an
CC       aryl-aryl bond formation yielding the six-ring indolocarbazole
CC       scaffold.
CC   -!- Along with RebC, a flavin-dependent hydroxylase, it also catalyzes
CC       the oxidative decarboxylation of both carboxyl groups.
CC   -!- The presence of RebC ensures that the only product is the
CC       rebeccamycin aglycone dichloroarcyriaflavin A.
CC   -!- The enzymes are similar, but not identical, to StaP and StaC, which
CC       are involved in the synthesis of staurosporine.
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