ID 1.14.11.31 DE thebaine 6-O-demethylase. CA 2-oxoglutarate + O2 + thebaine = CO2 + formaldehyde + neopinone + CA succinate. CC -!- Requires Fe(2+). CC -!- Catalyzes a step in morphine biosynthesis. CC -!- The product neopinione spontaneously rearranges to the more stable CC codeinone. CC -!- The enzyme also catalyzes the 6-O-demethylation of oripavine to CC morphinone, with lower efficiency. DR D4N500, DIOX1_PAPSO; D4N502, DIOX3_PAPSO; //