ENZYME entry: EC 1.14.11.4
Accepted Name |
Procollagen-lysine 5-dioxygenase.
|
Alternative Name(s) |
Lysine hydroxylase. |
Lysine,2-oxoglutarate 5-dioxygenase. |
Lysyl hydroxylase. |
Procollagen-lysine,2-oxoglutarate 5-dioxygenase. |
Reaction catalysed |
L-lysine-[procollagen] + 2-oxoglutarate + O(2) <=> (2S,5R)-5-hydroxy-L-lysine-[procollagen] + succinate + CO(2) |
Cofactor(s) |
Fe(2+); L-ascorbate.
|
Cross-references |
PROSITE | PDOC01028 ; PDOC51471 |
BRENDA | 1.14.11.4 |
EC2PDB | 1.14.11.4 |
ExplorEnz | 1.14.11.4 |
PRIAM enzyme-specific profiles | 1.14.11.4 |
KEGG Ligand Database for Enzyme Nomenclature | 1.14.11.4 |
IUBMB Enzyme Nomenclature | 1.14.11.4 |
IntEnz | 1.14.11.4 |
MEDLINE | Find literature relating to 1.14.11.4 |
MetaCyc | 1.14.11.4 |
Rhea expert-curated reactions | 1.14.11.4 |
UniProtKB/Swiss-Prot |
O77588, PLOD1_BOVIN; | P24802, PLOD1_CHICK; | Q02809, PLOD1_HUMAN; |
Q9R0E2, PLOD1_MOUSE; | Q5R9N3, PLOD1_PONAB; | Q63321, PLOD1_RAT; |
O00469, PLOD2_HUMAN; | Q9R0B9, PLOD2_MOUSE; | Q811A3, PLOD2_RAT; |
O60568, PLOD3_HUMAN; | Q9R0E1, PLOD3_MOUSE; | Q5R6K5, PLOD3_PONAB; |
Q5U367, PLOD3_RAT; | Q20679, PLOD_CAEEL; | Q9VTH0, PLOD_DROME; |
Q5UQC3, PLOD_MIMIV; |
|
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