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ENZYME entry: EC

Accepted Name
(S)-dichlorprop dioxygenase (2-oxoglutarate).
Alternative Name(s)
(S)-mecoprop dioxygenase.
2-oxoglutarate-dependent (S)-dichlorprop dioxygenase.
2-oxoglutarate-dependent (S)-mecoprop dioxygenase.
alpha-ketoglutarate-dependent (S)-dichlorprop dioxygenase.
Reaction catalysed
  • (S)-2-(4-chloro-2-methylphenoxy)propanoate + 2-oxoglutarate + O2 <=> 2-methyl-4-chlorophenol + CO2 + pyruvate + succinate
  • (S)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2 <=> 2,4-dichlorophenol + CO2 + pyruvate + succinate
The enzymes from the Gram-negative bacteria Delftia acidovorans MC1 and Sphingomonas herbicidovorans MH are involved in the degradation of the (S)-enantiomer of the phenoxyalkanoic acid herbicides mecoprop and dichlorprop.
PRIAM enzyme-specific profiles1.14.11.43
KEGG Ligand Database for Enzyme Nomenclature1.14.11.43
IUBMB Enzyme Nomenclature1.14.11.43
MEDLINEFind literature relating to
Rhea expert-curated reactions1.14.11.43
P83309, SDPA_DELAC;  Q700X4, SDPA_SPHHM;  

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